• It is well established that Shp can

  2021-05-25

  

  It is well established that Shp-2 can function as a substrate for several RTK, such as PDGF or EGFR [23], [36]. To test whether DDR1 recognizes Shp-2 as its substrate, we overexpressed a catalytically inactive Shp-2 mutant together with DDR1b in 293 cells [31]. Immunoprecipitation of Shp-2 followed

• In conclusion by investigating the cysteine protease transcr

  2021-05-25

  

  In conclusion, by investigating the cysteine protease transcriptome in soybean nodules, we found a number of cysteine proteases belonging to the C1 and C13 families strongly up-regulated following drought exposure such as C1 cysteine protease Glyma.14G085800 and C13 cysteine proteases Glyma.17G23070

• SAR405838 br Acknowledgments This research was supported by

  2021-05-25

  

  Acknowledgments This research was supported by grants from the Ministerio de Ciencia e Innovación (Grants SAF/FEDER 2010-17907; 2013-49076-P), Spain, Red de trastornos adictivos (RETICS RD12/0028//0003, Instituto de Salud Carlos III, Spain) and Fundación Séneca (15405/PI/10, Región de Murcia, Spa

• Multiple lines of evidence now indicate

  2021-05-25

  

  Multiple lines of evidence now indicate that mitochondrial decay is a fundamental factor that leads to alterations in energy metabolism in the aged heart (Hagen et al., 2002, Judge and Leeuwenburgh, 2007, Lesnefsky et al., 2001c). Nevertheless, the exact biochemical events that cause such an alterat

• In general up to date no study has considered thermodynamic

  2021-05-25

  

  In general, up to date, no study has considered thermodynamic modeling to estimate the tcY-NH2 of SO2 by different DESs. Since experimental measurements are time consuming and expensive, general and accurate theoretical models are vital to estimate SO2 solubilities in different DESs over wide ranges

• For any vector let and

  2021-05-25

  

  For any vector , let , and . For , let The information matrix for the partial likelihood at Eq. (2.2) can be expressed as It is well known that [Ala92]-p16 (84-103) synthesis under certain regularity conditions such as (A)–(D) in Andersen and Gill (1982), where and denote the maximum likelihood es

• Candesartan WM refers to the storage of information in

  2021-05-25

  

  WM refers to the storage of information in the context of processing, and coordination of elements into new structures (Oberauer, Süß, Wilhelm, & Wittman, 2003). Concerning the impact of WM on ISV facets, a strong negative association between WM and ex-Gaussian tau, suggesting that improved WM perfo

• The instructive precedent for galectin phosphorylation is hu

  2021-05-25

  

  The instructive precedent for galectin phosphorylation is human galectin-3 (hGal-3). Its serine modification by protein kinase CK1 in the N-terminal tail is relevant for nuclear export during the course of apoptosis regulation and contact formation with the neural cell adhesion molecule L1 , , , . T

• Perturbations in cell cycle are known to induce apoptosis Ou

  2021-05-25

  

  Perturbations in FSLLRY-NH2 australia are known to induce apoptosis. Our results show that a fraction of the DT40YB-1b+/− cells, in addition to becoming tetraploids, undergo apoptotic cell death. Similar observations linking polyploidy and apoptosis have been made in the past [23], [30], [31], [32]

• The causes of POD are complex and not

  2021-05-25

  

  The causes of POD are complex, and not entirely clear. Androsova et al, believed that the main molecular mechanism of POD is a central cholinergic deficiency caused by deregulation of cholinergic anti-inflammatory pathways leading to increased inflammation. The cholinergic anti-inflammatory pathway,

• As demonstrated by Mak and colleagues ER

  2021-05-25

  

  As demonstrated by Mak and colleagues, ERβ is known to be a part of the NFκB-HIF-1α signaling pathway during hypoxia as well as chronic inflammation of prostate (Mak et al., 2015), therefore in the next part of the study, we evaluated whether ZEA-induced ROS production is also associated with NFκB-H

• br Role of ERK signaling in preventive and therapeutic

  2021-05-24

  

  Role of ERK signaling in preventive and therapeutic potential of flavonoids in neurodegenerative diseases ERK is one of the main pharmacological targets of natural phenolic compounds and contributes to several therapeutic approaches including anti-atherogenic, anti-cancer, anti-colitis, anti-arth

• br Early developments Historically the advent of SMEPT can b

  2021-05-24

  

  Early developments Historically, the advent of SMEPT can be traced to the 1980′s, where the first example of localized prodrug conversion was achieved using a judiciously placed enzyme – in order to achieve a localized feed of 5-fluorouracil (5-FU). Immobilization of E. coli-derived cytosine deam

• In this study we investigated whether

  2021-05-24

  

  In this study, we investigated whether the Ednra signaling is involved in Hoxa9/Meis1-mediated leukemogenesis. We found an upregulation of Ednra in leukemic murine bone marrow (BM) Dexmedetomidine HCl overexpressing Hoxa9 and Meis1 compared to cells overexpressing Hoxa9 alone. We showed that overex

• The rate of protein degradation is often affected

  2021-05-24

  

  The rate of protein degradation is often affected by N-starvation [12], therefore, we examined the influence of N-starvation against the appearance of CEPs. N-starved cucumber cotyledons contained less amounts of protein and Rubisco, but the temporal changes in protein and Rubisco contents were simi

16296 records 678/1087 page Previous Next First page 上5页 676677678679680 下5页 Last page