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br Patients and methods br Discussion In this secondary endp
2019-04-20
Patients and methods Discussion In this opene handbag secondary endpoint analysis of the OPTION trial, we have shown that the addition of goserelin to neo(adjuvant) chemotherapy temporarily increased bone turnover during treatment and that this reverses over the next 6–12 months after complet
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br Management of warfarin during pacemaker implantable cardi
2019-04-20
Management of warfarin during pacemaker/implantable cardioverter defibrillator insertion Until recently, warfarin use was halted before PM/ICD insertion and the patient was bridged with intravenous (IV) unfractionated heparin or subcutaneous low-molecular-weight heparin (LMWH) if the thromboembol
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The increasing burden of NCDs poses an enormous threat to
2019-04-20
The increasing burden of NCDs poses an enormous threat to populations and health systems across the globe. The Sustainable Development Goals represent an important opportunity to integrate efforts to reduce the burden of NCDs and promote sustainable development. The recent identification of NCDs as
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Antenatal corticosteroids induce fetal lung
2019-04-20
Antenatal corticosteroids induce fetal lung maturation through the same biological mechanism in low-income settings as in high-income settings and reduce the need for neonatal mechanical ventilation. Although antenatal corticosteroids might not be a so-called magic bullet as a standalone vertical in
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br An estimated million babies are born
2019-04-20
An estimated 15 million babies are born preterm annually. Preterm birth complications account for more than 15% of deaths in children younger than 5 years and survivors often have long-term consequences with respect to their health, growth, and psychosocial functioning. The most beneficial interve
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Atrial fibrillation AF is the most common type
2019-04-19
Atrial fibrillation (AF) is the most common type of arrhythmia in developed countries. Its prevalence almost doubles with each decade of life [1], with a lifetime prevalence of 25% [2]. AF is also an important risk factor for mortality [3]. Along with stroke, heart failure (HF), which is a signific
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br Risk stratification in BrS Many
2019-04-19
Risk stratification in BrS Many risk markers have been reported in patients with high-risk BrS. Clinical markers include family history of sudden death at a young age (cytotoxicity assay in the right ventricle ( Treatment Asymptomatic patients Risk stratification and the optimal therapeutic
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A Cochrane review retained the three
2019-04-18
A 2015 Cochrane review retained the three community-based studies mentioned above and concluded that there was high-quality evidence of reduced risk of infection or omphalitis and death. The review also included two studies in which chlorhexidine was applied in a hospital setting: the above-describe
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br miRs and deregulation of bone remodeling Bone remodeling
2019-04-18
miRs and deregulation of bone remodeling Bone remodeling can be affected by osteotropic cancers at a distance (e.g. pre-metastatic niches) or in close proximity. It has been hypothesized that osteolytic cancer ekb-569 produce various osteolytic factors (e.g. PTHrP) that stimulate osteoblasts to s
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A meta analysis of seven observational
2019-04-18
A meta-analysis of seven observational studies, comparing dabigatran with warfarin, indicated that the ability of dabigatran to prevent ischemic stroke and bleeding outcomes is comparable to that of warfarin, which is consistent with the data obtained from the RE-LY trial [9]. These findings do not
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En su primera entrega para en
2019-04-18
En su primera entrega para “ en la pantalla” (3 de septiembre) Luis Cardoza establece matizadamente los parámetros sobre “la crítica” y lo que para él representa la cinematografía como expresión estética; los lineamientos observados de antemano explican sus continuas confrontaciones con el medio. Pu
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El t tulo del poema define
2019-04-18
El título del poema define una intertextualidad que se refuerza tipográficamente por medio de las cursivas del primer verso. La diferencia gráfica entre las palabras que integran este verso resalta el signo de la negación —el adverbio “no”— expresando una contradicción que culmina en los dos versos
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The fact that interstitial pneumonia
2019-04-18
The fact that interstitial pneumonia was induced at a low dose of bepridil (100mg/day) supports an immunoallergic mechanism rather than a pulmonary toxicity mechanism. In the present case, the dose of bepridil was lower than those in previously reported cases (150–400mg/day) [3] and it was given for
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br Methods As we were not privy to the
2019-04-18
Methods As we were not privy to the median year of enrolment, for all selected studies, the mean enrolment year ([start of enrolment+end of enrolment]/2) was calculated. If these dates were unavailable, the corresponding authors or sponsoring companies were contacted. When all methods to gather t
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Quiz algo que podr a unirlos en un
2019-04-18
Quizá algo que podría unirlos en un futuro sea una preocupación generalizada por la violencia, aunque los productos artísticos sobre el tema proceden de generaciones anteriores (por ejemplo, Te diría que fuéramos al río Bravo GSK503 llorar pero debes saber que ya no hay río ni llanto [2013] de Jorge
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