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Performing an ajmaline test in
2019-04-26
Performing an ajmaline test in children is problematic for 2 reasons. First, the test is apparently less sensitive in children than in adults. In fact, in 1 study, a repeat ajmaline challenge performed after puberty unmasked BrS in 23% of relatives with a previously negative drug test performed duri
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br En el ciclo de
2019-04-26
En el ciclo de novelas que de una forma u otra giran alrededor de la violencia y del narcotráfico, Cóbraselo caro atraviesa todos esos textos para preguntarse, por un lado, por la génesis de la violencia mexicana y por otro, para manifestar el deseo de una limpieza hallada en el modelo de mundo de
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It is recommended that pilsicainide be
2019-04-26
It is recommended that pilsicainide be administered over 10min, with 1.0mg/kg being the maximum daily dosage allowed. However, a single oral dose of pilsicainide has been shown to be effective, feasible and safe, and the single dose is always from 100 to 150mg [4,10]. Both the time to maximum drug c
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In addition we evaluated the left atrium left ventricle
2019-04-26
In addition, we evaluated the left atrium–left ventricle contraction sequence caused by the interatrial conduction delay. When we performed AV sequential pacing using the nominal AV delay setting, left atrial contractions were significantly delayed and were almost simultaneous with the left ventricu
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br Conclusion br Conflict of interest br
2019-04-26
Conclusion Conflict of interest Introduction Future challenges and conclusion In recent decades several anticancer drugs have been approved for the management and treatment of colorectal cancer. These drugs do not represent a revolution in the treatment of CRC. However, 5-FU has continue
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Efforts to estimate the global
2019-04-25
Efforts to estimate the global burden of typhoid fever can be traced to a meeting of the Pan American Health Organization in 1984 and publication of the outcome in 1986. Although an important first step, the 1984 study was recognised as having a number of limitations including provision of scanty me
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Vaccinated individuals might represent a safer source of hyp
2019-04-25
Vaccinated individuals might represent a safer source of hyperimmune serum. Two vaccine candidates will be tested soon in west Africa. If serum from vaccinated individuals has neutralising activity against the virus in cell models, this serum could be used as adjuvant therapy for EVD. In parallel, a
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br Methods br Results Globally CCI
2019-04-25
Methods Results Globally, CCI increased by 0·82 percent points a year, from 54·8% in 1994, to 71·2% in 2014 (CCI estimates at national level, stratified by wealth quintiles and place of residence, are presented in the appendix, pp 6–15). This gain was largely driven by low-income countries, wh
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br Acknowledgments We thank all the
2019-04-25
Acknowledgments We thank all the ultramarathon runners who participated in this study and all the doctors, nurses, and emergency medical technicians who provided professional care at the ultramarathon race. We also thank our colleagues at Soochow University, Taipei, Taiwan and the Chinese Taipei
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CaMKII phosphorylation of L type Ca
2019-04-25
CaMKII phosphorylation of L-type Ca2+channels alters channel gating by increasing open probability. CaMKII increases the window current of ICa-L, increasing the probability of the channels reopening during phase 2 BLU9931 and predisposing to early afterdepolarizations. Recently identified phosphoryl
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The increasing complexity and demands of the proper diagnosi
2019-04-25
The increasing complexity and demands of the proper diagnosis and management of patients with inherited cardiovascular disease create an opportunity for the development of specialized training for clinical electrophysiologists interested in the care of patients with inherited arrhythmias [229]. Such
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br Conclusion br Conflict of
2019-04-25
Conclusion Conflict of interest Introduction Radiofrequency catheter ablation has been established as an effective and curative therapy for Wolff-Parkinson-White Syndrome [1–4]. Therefore, prediction of the precise location of an accessory pathway (AP) prior to the ablation procedure is of
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Early repolarization ER is characterized
2019-04-25
Early repolarization (ER) is characterized by elevation of the QRS-ST junction (J point) and QRS notching or slurring (J wave) in multiple leads, especially the inferior and/or left precordial leads. Although this finding has been considered to be a benign ECG manifestation, Haïssaguerre et al repor
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La construcci n de las
2019-04-25
La construcción de las dimensiones de la identidad es un proceso que se desarrolla en el marco de las relaciones sociales, tanto EAI045 través de los debates internos como en los contactos extragrupales. En este sentido la identidad se ve modelada, también, por las estructuras del poder existentes.
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Atrial fibrillation is the most common atrial arrhythmia
2019-04-24
Atrial fibrillation is the most common atrial arrhythmia studied in BrS [3–14]. The prevalence of AF has been reported to be higher in patients with BrS than in the general telomerase inhibitors of the same age [15,16]. Earlier studies reported an approximately 10–50% prevalence of spontaneous, cli
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