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We conducted a retrospective analysis to
2019-05-07
We conducted a retrospective analysis to compare a BMD-alone strategy, versus BMD+FRAX® and BMD+FRAX®+TBS screening strategies. To our knowledge, this constitutes the first study to assess the relative contributions of FRAX® and TBS. In our cohort, FRAX®+BMD identified 9 (9%) additional patients at
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br Discussion SIS is a morphological
2019-05-07
Discussion SIS is a morphological characteristic of the basal interventricular septum that protrudes into the LV cavity. This cardiac malformation has generally been considered a natural part of aging without pathophysiological or clinical significance [5,6]. However, several studies demonstrated
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Heat shock facilitates the folding
2019-05-07
Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is
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useful handbook MIP binds to three different receptors
2019-05-06
MIP-1α binds to three different receptors: CCR1, CCR5 and CCR9. CCR1 and CCR5 are expressed on MM useful handbook and stromal cells. Inhibitors to CCR1 and CCR5 have been used to delineate the roles of each receptor in the myeloma bone marrow microenvironment[69]. Menu and colleagues demonstrated t
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Since BM impairs the balance between bone
2019-05-06
Since BM impairs the balance between bone formation and bone resorption, altered bone remodeling activities can be assessed directly by measuring the components of affected bone cells or indirectly by analyzing metabolic products released from the bone matrix by changed rates of bone formation or re
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br Conclusions br Conflict of interest br Introduction
2019-05-06
Conclusions Conflict of interest Introduction Radiofrequency (RF) catheter ablation is an established method of therapy for symptomatic supraventricular tachycardia (SVT). It has gained widespread acceptance for the treatment of accessory pathways in pediatric SVTs [1]. Accessory pathways a
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Cerrone et al reported that the
2019-05-06
Cerrone et al. reported that the mechanism of CPVT was due to delayed afterdepolarization‐induced triggered activity in a focal Purkinje network in a knock-in (RyR2) mouse [36]. In addition, chemical ablation of the RV endocardial cavity with Lugol׳s solution, which selectively destroys the Purkinje
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During a mean of months of follow
2019-05-06
During a mean of 41±29 months of follow-up, freedom from VT or VF was observed more frequently in the non-inducible group (24 of 30 (75%)) than in the inducible group (9 of 21 (43%), P=0.03). The estimated cumulative freedom from VT or VF was 88%, 83%, 75%, and 55% at the 1-, 2-, 3-, and 5-year foll
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La Proclama se alaba que las Fuerzas armadas asum
2019-05-06
La “Proclama” señalaba que las Fuerzas armadas asumían la conducción del Estado con el propósito de “terminar con el desgobierno, la corrupción y el flagelo subversivo.” En Guatemala, el “Comunicado Urgente al Pueblo” inmediatamente después del golpe del 23 de marzo de 1982 decía que: “El ejército
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TAPI-1 Evidence supporting the benefit of dexrazoxane as car
2019-05-06
Evidence supporting the benefit of dexrazoxane as cardioprotective therapy in adults with acute leukemia are scant [11]. However, there is a significant need for cardioprotective therapy, particularly in older individuals with preexisting cardiovascular disorders and/or prior anthracycline exposure,
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hoechst 33342 IL IL is another potential inhibitor of OBL di
2019-05-06
IL-7: IL-7 is another potential inhibitor of OBL differentiation in MM that induces RANKL production by T lymphocytes [113] and mediates MM-induced OBL inhibition by down-regulating RUNX2 transcriptional activity [93]. IL-7 levels are increased in the marrow of MM patients and that IL-7 inhibited bo
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However it should be noted
2019-05-06
However, it should be noted that large proportion of patients develop at least one SRE after BTAs vasopressin receptor antagonists (74/155, 48%) appearing to be in keeping with the results of randomised BTA trials [3–6]. Indeed, for those patients who had not had an SRE prior to commencing a BTA, t
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The review Bile acid receptor link nutrient sensing to
2019-05-06
The review “Bile hdac inhibitor receptor link nutrient sensing to metabolic regulation” by Li and Li is focused on bile acid receptors in the regulation of hepatic glucose and lipid metabolism and inflammation. Cholestasis and NAFLD are inflammatory liver diseases. Triglycerides are non-toxic, but
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En este art culo se observar n
2019-05-05
En este artículo se observarán ciertos puntos de los capítulos IX y X de Paradiso, donde el autor claramente se rehúsa pop over to this site definir a sus personajes y sus discursos, para plantear interrogantes y momentos paradigmáticos de esta imposibilidad clasificatoria que era el objetivo (o uto
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Respecto a las libertades propuestas por Dahl expresi
2019-05-05
Respecto molecular mass calculator las libertades propuestas por Dahl (expresión, información y asociación) señala que no son suficientes, podrían tenerse en cuenta otras, o explicitar sus alcances, lo cual constituye un problema difícil de asumir. Él mismo no propone una lista de libertades. En tod
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